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J Agric Food Chem. 2015 Jun 3;63(21):5141-5. doi: 10.1021/jf505254y. Epub 2015 Jan 28.

Antibiotic residue monitoring results for pork, chicken, and beef samples in Vietnam in 2012-2013.

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†Osaka Prefectural Institute of Public Health, 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.
‡Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
§Institute of Public Health, 159 Hung Phu, District 8, Ward 8, Ho Chi Minh City, Vietnam.
#Pasteur Institute, 8-10 Pasteur Xuong Huan Ward, Nha Trang City, Vietnam.
⊥Global Collaboration Center, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.


A monitoring plan of residual antibiotics in food of animal origin was conducted in Vietnam from 2012 to 2013. Meat samples were collected from slaughterhouses and retail stores in Ho Chi Minh City and Nha Trang. A total of 28 antibiotics were analyzed using a LC-MS/MS screening method. Sulfonamides, fluoroquinolones, and tilmicosin were detected in some of the samples. Sulfaclozine and fluoroquinolones were mainly detected in chicken samples, and sulfamethazine was mainly detected in pork samples. High levels of sulfonamide residues, ranging between 2500 and 2700 μg/kg sulfaclozine and between 1300 and 3600 μg/kg sulfamethazine, were present in two chicken and three pork samples, respectively. Tilmicosin was detected at ranges of 150-450 μg/kg in 10 chicken samples. Positive percentages were 17.3, 8.8, and 7.4% for chicken, pork, and beef, respectively, for an average of 11.9%. The results suggest an appropriate withdrawal period after drug administration had not been observed in some livestock.


Vietnam; food; liquid chromatography−tandem mass spectrometry; residual antibiotics

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