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Maturitas. 2015 Mar;80(3):296-301. doi: 10.1016/j.maturitas.2014.12.006. Epub 2014 Dec 25.

Vulvo-vaginal atrophy: a new treatment modality using thermo-ablative fractional CO2 laser.

Author information

1
Department of Obstetrics and Gynaecology, University Hospital "P. Giaccone", Palermo, Italy.
2
Department of Public Health, Experimental and Forensic Medicine, Unit of Histology and Embryology University of Pavia, Pavia, Italy.
3
Department of Obstetrics and Gynaecology, University Hospital "P. Giaccone", Palermo, Italy. Electronic address: forlani81@gmail.com.
4
Department of Human Pathology, School and Division of Allergy and Clinical Immunology, University of Messina, Messina, Italy.

Abstract

OBJECTIVE:

To evaluate the efficacy and feasibility of thermo-ablative fractional CO2 laser for the treatment of symptoms related to vulvo-vaginal atrophy (VVA) in post-menopausal women.

METHODS:

From April 2013 to December 2013, post-menopausal patients who complained of one or more VVA-related symptoms and who underwent vaginal treatment with fractional CO2 laser were enrolled in the study. At baseline (T0) and 30 days post-treatment (T1), vaginal status of the women was evaluated using the Vaginal Health Index (VHI), and subjective intensity of VVA symptoms was evaluated using a visual analog scale (VAS). At T1, treatment satisfaction was evaluated using a 5-point Likert scale.

RESULTS:

During the study period, a total of 48 patients were enrolled. Data indicated a significant improvement in VVA symptoms (vaginal dryness, burning, itching and dyspareunia) (P<0.0001) in patients who had undergone 3 sessions of vaginal fractional CO2 laser treatment. Moreover, VHI scores were significantly higher at T1 (P<0.0001). Overall, 91.7% of patients were satisfied or very satisfied with the procedure and experienced considerable improvement in quality of life (QoL). No adverse events due to fractional CO2 laser treatment occurred.

CONCLUSION:

Thermo-ablative fractional CO2 laser could be a safe, effective and feasible option for the treatment of VVA symptoms in post-menopausal women.

KEYWORDS:

Laser treatment; Menopause; Vulvo-vaginal atrophy

PMID:
25596815
DOI:
10.1016/j.maturitas.2014.12.006
[Indexed for MEDLINE]

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