Long-term results of surgical angioplasty for left main coronary artery stenosis: 18-year follow-up

J Cardiothorac Surg. 2015 Jan 17:10:6. doi: 10.1186/s13019-015-0209-x.

Abstract

Background: The aim of this study was to determine the long-term outcomes of surgical angioplasty for left main coronary artery (SA-LMCA) stenosis.

Methods: We retrospectively analyzed data from 24 consecutive patients (mean age, 55 years; male/female, 12/12) who underwent a surgical angioplasty for the left main coronary artery (LMCA) stenosis at our institution between 1995 and 2002. We used autologous pericardium in 7 patients and bovine pericardium in 17 patients as a patch. We evaluated the late mortality and major adverse cardiac events (MACE) rate.

Results: There was no operative mortality. Control coronary angiography exhibited wide open and funnel-shaped LMCA in all patients. One patient was lost to follow-up. During the mean follow-up of 167 months, there were 3 sudden cardiac deaths, 4 non-cardiac related deaths, and 9 MACE with one death at reoperation. The Kaplan-Meier method identified freedom from cardiac death in 95.7, 87.0, and 82.4% of the patients, and freedom from MACE in 91.3, 69.6, and 57.7% of the patients at 5, 10, and 15 years, respectively.

Conclusions: This study demonstrated that the long-term outcomes of SA-LMCA with a pericardial patch are acceptable compared to those of coronary artery bypass grafting, despite the controversy over the indications and the patch material used.

MeSH terms

  • Adult
  • Aged
  • Angioplasty / instrumentation*
  • Angioplasty / methods
  • Coronary Angiography
  • Coronary Artery Bypass*
  • Coronary Stenosis / mortality
  • Coronary Stenosis / pathology
  • Coronary Stenosis / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Pericardium / surgery
  • Postoperative Complications
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome