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Chem Commun (Camb). 2015 Feb 18;51(14):2939-42. doi: 10.1039/c4cc08854a.

A multiplex fluorophore molecular beacon: detection of the target sequence using large Stokes shift and multiple emission signal properties.

Author information

1
Department of Chemistry, Chonbuk National University, Jeonju 561-756, South Korea. yseo@jbnu.ac.kr.

Abstract

We have developed a multiplex fluorophore molecular beacon () with fluorophores located at its end to produce unique FRET (Fluorescence Resonance Energy Transfer). It exhibited diverse fluorescence properties depending on the mixing pattern, such as large Stokes shift emission and multiple colors, namely, blue, green and red using one excitation wavelength. Our also worked in probing a target perfect matched sequence with exonuclease III.

PMID:
25588113
DOI:
10.1039/c4cc08854a
[Indexed for MEDLINE]

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