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Contact Dermatitis. 2015 Mar;72(3):172-7. doi: 10.1111/cod.12326. Epub 2015 Jan 12.

Sunflower seeds as eliciting agents of Compositae dermatitis.

Author information

1
Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Sdr. Boulevard 29, DK-5000, Odense C, Denmark.

Abstract

BACKGROUND:

Sunflowers may cause dermatitis because of allergenic sesquiterpene lactones (SLs). Contact sensitization to sunflower seeds has also been reported, but the allergens are unknown.

OBJECTIVES:

To analyse sunflower seeds for the presence of SLs and to assess the prevalence of sunflower sensitization in Compositae-allergic individuals.

PATIENTS/MATERIALS/METHODS:

Sunflower-sensitive patients were identified by aimed patch testing. A dichloromethane extract of whole sunflower seeds was analysed by liquid chromatography-mass spectrometry and high-performance liquid chromatography.

RESULTS:

The prevalence of sensitivity to sunflower in Compositae-allergic individuals was 56%. A solvent wash of whole sunflower seeds yielded an extract containing SLs, the principal component tentatively being identified as argophyllin A or B, other SLs being present in minute amounts.

CONCLUSIONS:

The concentration of SLs on the sunflower seeds is considered high enough to elicit dermatitis in sensitive persons, and it seems appropriate to warn Compositae-allergic subjects against handling sunflower seeds.

KEYWORDS:

Asteraceae; Compositae; Helianthus annuus; allergic contact dermatitis; patch testing; sunflower seeds

PMID:
25581855
DOI:
10.1111/cod.12326
[Indexed for MEDLINE]

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