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Asian J Androl. 2015 Mar-Apr;17(2):201-5. doi: 10.4103/1008-682X.143736.

Alternatives to testosterone replacement: testosterone restoration.

Author information

1
Department of Urology, Albany Medical College, Albany, New York, USA.

Abstract

The European Male Aging Study has demonstrated that the hypogonadism of male aging is predominantly secondary. Theoretically with appropriate stimulation from the pituitary, the aging testis should be able to produce eugonadal levels of testosterone. The strategies for the treatment of late onset hypogonadism (LOH) have focused on replacement with exogenous testosterone versus restoration of endogenous production. The purpose of this article is to review existing peer-reviewed literature supporting the concept of restoration of endogenous testosterone in the treatment of LOH.

PMID:
25578932
PMCID:
PMC4650464
DOI:
10.4103/1008-682X.143736
[Indexed for MEDLINE]
Free PMC Article

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