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Int J Pediatr Otorhinolaryngol. 2015 Feb;79(2):240-5. doi: 10.1016/j.ijporl.2014.12.018. Epub 2014 Dec 22.

Complications of adenotonsillectomy for obstructive sleep apnea in school-aged children.

Author information

1
Department of Pediatrics, Sleep Center, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States. Electronic address: Konstantis@chop.edu.
2
Biostatistics Core, The Clinical and Translational Research Center, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.
3
Department of Otolaryngology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.
4
Department of Otolaryngology, University of Michigan, Ann Arbor, MI, United States.
5
Department of Otolaryngology, UT Southwestern Medical Center, Dallas, TX, United States; Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States.
6
Department of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
7
Department of Pediatrics, Rainbow Babies & Children's Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, United States.
8
Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
9
Department of Pediatrics, University of Michigan, Ann Arbor, MI, United States; Department of Neurology, University of Michigan, Ann Arbor, MI, United States.
10
Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
11
Department of Pediatrics, Children's Hospital at Montefiore and Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States.
12
Department of Pediatrics and Internal Medicine, Cardinal Glennon Children's Medical Center, Saint Louis University, St Louis, MO, United States.
13
Department of Pediatrics, Sleep Center, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.

Abstract

INTRODUCTION:

Adenotonsillectomy is the treatment of choice for most children with obstructive sleep apnea syndrome, but can lead to complications. Current guidelines recommend that high-risk children be hospitalized after adenotonsillectomy, but it is unclear which otherwise-healthy children will develop post-operative complications. We hypothesized that polysomnographic parameters would predict post-operative complications in children who participated in the Childhood AdenoTonsillectomy (CHAT) study.

METHODS:

Children in the CHAT study aged 5-9 years with apnea hypopnea index 2-30/h or obstructive apnea index 1-20/h without comorbidities other than obesity/asthma underwent adenotonsillectomy. Associations between demographic variables and surgical complications were examined with Chi square and Fisher's exact tests. Polysomnographic parameters between subjects with/without complications were compared using Mann-Whitney tests.

RESULTS:

Of the 221 children (median apnea hypopnea index 4.7/h, range 1.2-27.7/h; 31% obese), 16 (7%) children experienced complications. 3 (1.4%) children had respiratory complications including pulmonary edema, hypoxemia and bronchospasm. Thirteen (5.9%) had non-respiratory complications, including dehydration (4.5%), hemorrhage (2.3%) and fever (0.5%). There were no statistically significant associations between demographic parameters (gender, race, and obesity) or polysomnographic parameters (apnea hypopnea index, % total sleep time with SpO2<92%, SpO2 nadir, % sleep time with end-tidal CO2>50Torr) and complications.

CONCLUSIONS:

This study showed a low risk of post-adenotonsillectomy complications in school-aged healthy children with obstructive apnea although many children met published criteria for admission due to obesity, or polysomnographic severity. In this specific population, none of the polysomnographic or demographic parameters predicted post-operative complications. Further research could identify the patients at greatest risk of post-operative complications.

KEYWORDS:

Adenotonsillectomy; Childhood AdenoTonsillectomy study; Obstructive sleep apnea syndrome; Polysomnography

PMID:
25575425
PMCID:
PMC4319650
DOI:
10.1016/j.ijporl.2014.12.018
[Indexed for MEDLINE]
Free PMC Article

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