Introduction: The objective of this study is to identify computed tomography (CT) features of local recurrence (LR) after stereotactic body radiation therapy (SBRT) for lung cancer.
Methods: Two hundred eighteen patients underwent SBRT for lung cancer from January 1st, 2006 to March 1st, 2011. Signs of LR recorded: opacity with new bulging margin, opacification of air bronchograms, enlarging pleural effusion, new or enlarging mass, and increased lung density at the treatment site.
Results: A new bulging margin at the treatment site was the only feature significantly associated with LR (P<.005).
Conclusion: Most CT features classically associated with LR following conventional radiation therapy are unreliable for predicting LR following SBRT.
Keywords: Computed tomography; Local recurrence; Lung cancer; Stereotactic body radiation therapy.
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