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Pak J Pharm Sci. 2015 Jan;28(1):43-7.

Clinical efficacy of polyherbal formulation Eezpain spray for muscular pain relief.

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Department of Research and Development, Herbion Pakistan (Pvt.) Limited, Plot 30, Sector 28, Korangi Industrial Area, Karachi, Pakistan.
Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan.


The topical herbal formulation Eezpain spray consisting of natural ingredients that have been clinically proved for its analgesic and anti-inflammatory activity. The designed formulation on application knee and wrist joints, back of neck and shoulder, forearms and lower back exhibited significant efficacy. A total of 20 subjects both male and female applied Eezpain spray consisting of Gaultheria oil, Eucalyptus oil, Turpentine oil, Clove Oil, Menthol and Camphor. All the active materials are cited that these have analgesic activity in myalgia and neuralgia. The study design was prospective and opens as pilot study followed the inclusion and exclusion criteria. All the sign and symptoms were noted at baseline and at the end of 14 days treatment performance was evaluated. The statistical analysis was done by using Microsoft Excel2007 and SPSS version 18.0. It is concluded that Eezpain spray has shown efficacy in mild to moderate cases on applying locally to the affected parts to relieve pain from different ailments.

[Indexed for MEDLINE]

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