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Comput Methods Programs Biomed. 2015 Feb;118(2):124-33. doi: 10.1016/j.cmpb.2014.12.001. Epub 2014 Dec 9.

Enhancing classification accuracy utilizing globules and dots features in digital dermoscopy.

Author information

1
Department of Digital Systems, University of Piraeus, Greece. Electronic address: imaglo@unipi.gr.
2
University of Thessaly, Department of Computer Science and Biomedical Informatics, Greece.

Abstract

The interest in image dermoscopy has been significantly increased recently and skin lesion images are nowadays routinely acquired for a number of skin disorders. An important finding in the assessment of a skin lesion severity is the existence of dark dots and globules, which are hard to locate and count using existing image software tools. In this work we present a novel methodology for detecting/segmenting and count dark dots and globules from dermoscopy images. Segmentation is performed using a multi-resolution approach based on inverse non-linear diffusion. Subsequently, a number of features are extracted from the segmented dots/globules and their diagnostic value in automatic classification of dermoscopy images of skin lesions into melanoma and non-malignant nevus is evaluated. The proposed algorithm is applied to a number of images with skin lesions with known histo-pathology. Results show that the proposed algorithm is very effective in automatically segmenting dark dots and globules. Furthermore, it was found that the features extracted from the segmented dots/globules can enhance the performance of classification algorithms that discriminate between malignant and benign skin lesions, when they are combined with other region-based descriptors.

KEYWORDS:

Dark dot segmentation; Dermoscopy images; Globule segmentation; Image classification; Melanoma detection; Skin lesions

PMID:
25540998
DOI:
10.1016/j.cmpb.2014.12.001
[Indexed for MEDLINE]

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