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J Am Soc Hypertens. 2015 Jan;9(1):38-47. doi: 10.1016/j.jash.2014.10.002. Epub 2014 Oct 16.

RESPeRATE: the role of paced breathing in hypertension treatment.

Author information

1
Department of Nephrology, Wolfson Medical Center, Holon, Israel; The Brunner Institute for Cardiovascular Research, Tel Aviv University and Wolfson Medical Center, Holon, Israel.
2
The Brunner Institute for Cardiovascular Research, Tel Aviv University and Wolfson Medical Center, Holon, Israel; Department of Medicine, Wolfson Medical Center, Holon, Israel. Electronic address: zimlich@post.tau.ac.il.

Abstract

Despite a good adherence to lifestyle modifications and antihypertensive drugs, hypertension remains resistant in more than one-third of patients, thus creating the need for additional strategies, including non-pharmacologic approaches. Slow and deep breathing ("paced breathing") associated in the past with meditation has a direct antihypertensive effect by increasing baroreflex sensitivity. With the method of guiding the pace of breathing, a US Food and Drug Administration-certified device, RESPeRATE, may offer an easy, efficient, inexpensive, and noninvasive option for treating hypertension. Multiple studies showed a significant reduction of blood pressure when RESPeRATE was evaluated in a home and office setting. In conclusion, this review outlines the pathophysiologic background of paced respiration, describes RESPeRATE clinical trials, and presents briefly other guided breathing alternatives.

KEYWORDS:

Baroreflex sensitivity; blood pressure; hypertension treatment; paced breathing

Comment in

PMID:
25539897
DOI:
10.1016/j.jash.2014.10.002
[Indexed for MEDLINE]

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