Format

Send to

Choose Destination
Ann Hepatol. 2015 Jan-Feb;14(1):132-6.

Mycobacterium abscessus pulmonary infection during hepatitis C treatment with telaprevir, peginterferon and ribavirin.

Author information

1
Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile.
2
Afiliacja Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile.
3
Department of Radiology, School of Medicine, Pontificia Universidad Católica de Chile.
4
Department of Infectious Diseases, School of Medicine, Pontificia Universidad Católica de Chile.

Abstract

The first generation protease inhibitors has been the mainstay of hepatitis C treatment for the last couple of years, showing marked improvement in sustained virological response, but also increased side effects. Infection has emerged as a common complication of telaprevir and boceprevir in combination with peginterferon and ribavirin, usually caused by common pathogens. We present the case of a 65 years old man who developed a Mycobacterium abscessus pulmonary infection during treatment with telaprevir, peginterferon and ribavirin. The patient was successfully treated with amikacin, imipenem and chlarithromycin. The present case is relevant for increasing awareness for recognition of opportunistic infections and particularly nontuberculous mycobacterial infections in patients receiving triple therapy for chronic hepatitis C, especially in cirrhotic subjects who develop significant lymphopenia.

PMID:
25536652
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for IndexCopernicus
Loading ...
Support Center