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JAMA. 2014 Dec 24-31;312(24):2678-9. doi: 10.1001/jama.2014.12839.

Antibiotics for acute bronchitis.

Author information

1
HRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland Medical School, Dublin.
2
Palo Alto Medical Foundation, Dublin Center, Dublin, California.

Erratum in

Abstract

CLINICAL QUESTION:

Are antibiotics associated with improved outcomes in patients with acute bronchitis?

BOTTOM LINE:

Prescribing antibiotics for acute bronchitis was associated with reduced overall and nighttime cough and with an approximately half-day reduction in duration of cough, in days feeling ill, and in days with impaired activities. However, at follow-up, there were no significant differences in patients receiving antibiotics compared with those receiving placebo in overall clinical improvements or limitations in work or other activities. There was a significant increase in adverse effects in the antibiotic group, particularly gastrointestinal symptoms.

Comment on

PMID:
25536260
DOI:
10.1001/jama.2014.12839
[Indexed for MEDLINE]

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