Format

Send to

Choose Destination
Nat Rev Neurol. 2015 Feb;11(2):72-4. doi: 10.1038/nrneurol.2014.250. Epub 2014 Dec 23.

Motor neuron disease in 2014. Biomarkers for ALS--in search of the Promised Land.

Author information

1
Rita Levi Montalcini' Department of Neuroscience, University of Torino, via Cherasco 15, 10126 Torino, Italy.
2
Neuromuscular Diseases Research Unit, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.

Abstract

The past year has seen some extraordinary activity in clinical amyotrophic lateral sclerosis (ALS) research. Two trials were completed, with negative results, but the discovery of novel ALS-associated genes, and body fluid and imaging biomarkers warrants cautious optimism. Here, we provide a snapshot of some of the main findings in 2014.

PMID:
25534912
PMCID:
PMC5185468
DOI:
10.1038/nrneurol.2014.250
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center