Hearts were isolated at 3 hours post-resection, 21 dpr and 7 dpr. A. Relative heart weights at 3 hours post-resection. (Sham: n=21, Moderate: n=25, Large: n=9). *p<0.05,***p<0.001. B. Representative trichrome stainings of sections from hearts at 21 dpr. Apical regions of the left ventricle are shown. Scar tissue stains blue. Scale bar: 100 µm. C. Quantification of scar incursion into the left ventricular wall (prop.=proportion). (Sham: n=6, Moderate: n=23, Large: n=10). *p<0.05. See also, . D. Representative immunofluorescent stainings of sections at 7 dpr for phospho-H3 (pH3) and cardiac troponin t (cTnnT). Arrowheads indicate pH3+/cTnnT+ cells. E. Quantification of pH3+/cTnnT+ cells. (Sham: n=6, Moderate: n=8, Large: n=8). *p<0.05,**p<0.01, ns=non-significance.