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Future Oncol. 2014 Dec;10(15):2311-7. doi: 10.2217/fon.14.158.

Chest wall and rib irradiation and toxicities of early-stage lung cancer patients treated with CyberKnife stereotactic body radiotherapy.

Author information

1
Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University, 11100 Euclid Avenue, LTR B181, Cleveland, OH 44106, USA.

Abstract

AIM:

The aim of the study is to evaluate the chest wall and rib toxicities in primary lung cancer patients treated with CyberKnife-based stereotactic body radiotherapy.

MATERIALS & METHODS:

In this study, data were collected from the 118 patients, of which 25 patients who had longer follow-up (mean: 21.9 months) were considered. Studied parameters were maximum point dose, doses to 1-100 cm(3) of chest wall and 1-10 cm(3) of ribs.

RESULTS:

Three patients developed chest wall pain (grade I). 25 studied patients, on average, received 27.7 Gy to 30 cm(3) of chest wall and 50.4 Gy to 1 cm(3) of rib. Nine patients had more than 30 Gy dose to 30 cm(3) of chest wall. No rib bone fracture was found.

CONCLUSION:

No correlations of chest wall pain and volume of irradiation were found.

KEYWORDS:

CyberKnife; chest pain; chest wall toxicity; rib fracture; stereotactic body radiotherapy

PMID:
25525841
DOI:
10.2217/fon.14.158
[Indexed for MEDLINE]

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