Format

Send to

Choose Destination
Clin Ter. 2014;165(6):e395-400. doi: 10.7417/CT.2014.1780.

Safety and prolonged efficacy of Botulin Toxin A in primary hyperhidrosis.

Author information

1
Dermatology Clinic, 'Sapienza' University of Rome, Italy.

Abstract

BACKGROUND:

Hyperhidrosis is a condition characterized by generalized or localized hyperfunction of the eccrine sweat glands with a deep negative impact on patient's quality of life.

OBJECTIVES:

To evaluate the efficacy and the safety of Botulin Toxin A (BTX-A) intradermal injection in the treatment of primary axillary and palmar hyperhidrosis, investigating symptoms-free period, and the subjective improving of quality life.

MATERIALS AND METHODS:

50 consecutive patients with primary hyperhidrosis were evaluated detecting age, gender, hyperhidrosis onset period, disease duration and years of treatment with BTX-A, Minor's iodine test, Hyperhidrosis Disease Severity Scale (HDSS), Dermatology Life Quality Index (DLQI).

RESULTS:

The treatment is significantly effective both for axillae and palms: the majority of the patients improved their HDSS and Minor's scores from a value of 4 in the two tests, to values of 1 (HDSS) and 0 (Minor test). Patients reported a duration of symptoms relief from 4 to 12 months, with a mean of 5.68 months; specifically, we have observed that the axillary group experienced a longer symptoms-free period (mean RFS 7.2 months) than the palmar group (mean: RFS 4.27 months).

CONCLUSIONS:

Authors suggest that BTX-A is a safe, easy, and fast procedure for the treatment of primary axillary and palmar hyperhidrosis.

KEYWORDS:

Axillary hyperhidrosis; Botulinum toxin; Palmar hyperhidrosis

PMID:
25524193
DOI:
10.7417/CT.2014.1780
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Societa Editrice Universo, srl
Loading ...
Support Center