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AIDS Res Hum Retroviruses. 2015 Mar;31(3):353-7. doi: 10.1089/AID.2014.0244. Epub 2015 Jan 21.

Genetic characterization of near full length SIVdrl genomes from four captive drills (Mandrillus leucophaeus).

Author information

1
1 Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy , Frankfurt, Germany .

Abstract

We sequenced near full length SIVdrl genomes from four captive drills (Mandrillus leucophaeus). All four animals were born in captivity in German zoos. Although serologically SIV negative before acquisition in zoo A in 2008 and 2009, during a routine analysis all four animals were determined to be SIV antibody positive in 2011. Comparisons of the four new SIVdrl sequences showed high identity among each other (90.7-97.7% in env) and to the only published full length sequence SIVdrl FAO (90.5-92.8% in env), which is also derived from a captive drill. SIVdrl infections seem to be highly prevalent in captive drills, probably resulting from frequent animal transfers between the zoos in an effort to maintain this highly endangered species and its genetic diversity. This should be kept in mind as SIVdrl may be transmitted to uninfected animals in open groups and potentially also to animal keepers having contact with these nonhuman primates.

PMID:
25523403
DOI:
10.1089/AID.2014.0244
[Indexed for MEDLINE]

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