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Semin Neurol. 2014 Nov;34(5):496-503. doi: 10.1055/s-0034-1396003. Epub 2014 Dec 17.

Rehabilitation of poststroke cognition.

Author information

Department of Health Psychology, University of Missouri, Columbia, Missouri.
Department of Psychological Sciences and Brain Imaging Center, University of Missouri, Columbia, Missouri.
Stroke Rehabilitation Research, Kessler Foundation, West Orange, New Jersey.


Given the increasing rates of stroke and our aging population, it is critical that we continue to foster innovation in stroke rehabilitation. Although there is evidence supporting cognitive rehabilitation in stroke, the set of cognitive domains effectively addressed to date represents only a small subset of the problems experienced by stroke survivors. Further, a gap remains between investigational treatments and our evolving theories of brain function. These limitations present opportunities for improving the functional impact of stroke rehabilitation. The authors use a case example to encourage the reader to consider the evidence base for cognitive rehabilitation in stroke, focusing on four domains critical to daily life function: (1) speech and language, (2) functional memory, (3) executive function and skilled learned purposive movements, and (4) spatial-motor systems. Ultimately, they attempt to draw neuroscience and practice closer together by using translational reasoning to suggest possible new avenues for treating these disorders.

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