Objective: A method for simultaneous determination of 35 plasticizers in drinking water by gas chromatography-mass spectrometry (GC/MS)was developed.
Method: The samples were extracted with ethyl acetateand, and separated by DB-5MS column. The identification and quantification were performed by GC/MS in selected ion monitoring (SIM) mode.
Results: The calibration curves of plasticizers showed linearity in linear range of 0. 05 - 2. 0 mg/L, and the correlation coefficients (r2 ) higher than 0.995. The limits of detection of the method were 0. 0001 -0. 001 mg/L (S/N =3), and the limit quantification were 0. 0004 - 0. 004 mg/L (S/N = 10). The average recoveries of 35 plasticizers in drinking water ranged from 65% to 118% with the relative standard deviations (RSDs, n =6) of 1.7% - 11. 5%.
Conclusion: The method is suitable for determination of 35 plasticizers simultaneously in drinking water with easy operation, high accuracy and precision.