Plasmon-coupled gold nanospheres for two-photon imaging and photoantibacterial activity

Adv Healthc Mater. 2015 Apr 2;4(5):674-8. doi: 10.1002/adhm.201400524. Epub 2014 Dec 15.

Abstract

Positively charged Au nanospheres are found to form aggregates on the bacterial surface, resulting in significantly enhanced two-photon photoluminescence (TPPL). The enhanced TPPL is successfully utilized to image bacterial cells in the NIR region. In addition, these Au nanospheres effectively eradicate the bacterial cells by laser pulses in the same NIR region due to the photothermal effect.

Keywords: Au nanospheres; imaging; photoantibacterial; plasmon resonance; two-photon excitation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Cell Line
  • Gold / chemistry*
  • Gold / pharmacology
  • Humans
  • Microbial Viability / drug effects*
  • Nanospheres / chemistry*
  • Staphylococcus aureus / drug effects
  • Surface Plasmon Resonance / methods*

Substances

  • Anti-Bacterial Agents
  • Gold