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Arch Virol. 1989;106(3-4):213-20.

Denaturation of poliovirus procapsids.

Author information

1
Department of Microbiology and Hygiene, Vrije Universiteit Brussel, Belgium.

Abstract

The denaturation of poliovirus procapsids at pH 6.5 was studied, both in the frozen and liquid condition. Denaturation involved alteration of antigenic and physical features (isoelectric pH, alkali dissociability, sedimentation coefficient). Magnesium was a stabilizing factor, and the sedimentation coefficient was the most denaturation-sensitive feature.

PMID:
2549918
[Indexed for MEDLINE]

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