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Microbes Infect. 2015 Feb;17(2):109-17. doi: 10.1016/j.micinf.2014.11.012. Epub 2014 Dec 11.

Development of therapeutics for treatment of Ebola virus infection.

Author information

1
Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China.
2
Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China. Electronic address: lul@fudan.edu.cn.
3
Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China; Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA. Electronic address: shibojiang@fudan.edu.cn.

Abstract

Ebola virus infection can cause Ebola virus disease (EVD). Patients usually show severe symptoms, and the fatality rate can reach up to 90%. No licensed medicine is available. In this review, development of therapeutics for treatment of Ebola virus infection and EVD will be discussed.

KEYWORDS:

Antibody; Ebola virus; Ebola virus disease; Small-molecule compounds; Therapeutics; Treatment

PMID:
25498866
DOI:
10.1016/j.micinf.2014.11.012
[Indexed for MEDLINE]

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