Right superior temporal gyrus volume in adolescents with a history of suicide attempt

Br J Psychiatry. 2015 Apr;206(4):339-40. doi: 10.1192/bjp.bp.114.151316. Epub 2014 Dec 11.

Abstract

The extent to which observed differences in emotion processing and regulation neural circuitry in adolescents with a history of suicide attempt are paralleled by structural differences is unknown. We measured brain cortical thickness and grey- and white-matter volumes in 100 adolescents: 28 with a history of suicide attempt and major depressive disorder (MDD); 31 with a history of MDD but no suicide attempt; and a healthy control group (n = 41). The first group compared with controls showed reduction in grey-matter volume in the right superior temporal gyrus (BA38), a region important for social emotion processing.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Depressive Disorder, Major / physiopathology*
  • Emotions
  • Gray Matter / anatomy & histology*
  • Gyrus Cinguli / anatomy & histology*
  • Humans
  • Magnetic Resonance Imaging
  • Organ Size
  • Suicide, Attempted / psychology*
  • Temporal Lobe / anatomy & histology*
  • White Matter / anatomy & histology*