Format

Send to

Choose Destination
Behav Sci (Basel). 2014 Dec 8;4(4):511-527.

Assessing Treatment-Resistant Posttraumatic Stress Disorder: The Emory Treatment Resistance Interview for PTSD (E-TRIP).

Author information

1
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, 3rd Floor, Atlanta, GA 30329, USA. bdunlop@emory.edu.
2
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, 3rd Floor, Atlanta, GA 30329, USA. jlk399@drexel.edu.
3
Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. cyoungn@emory.edu.
4
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, 3rd Floor, Atlanta, GA 30329, USA. brothba@emory.edu.

Abstract

Patients with posttraumatic stress disorder (PTSD) who fail to respond to established treatments are at risk for chronic disability and distress. Although treatment-resistant PTSD (TR-PTSD) is a common clinical problem, there is currently no standard method for evaluating previous treatment outcomes. Development of a tool that could quantify the degree of resistance to previously provided treatments would inform research in patients with PTSD. We conducted a systematic review of PTSD treatment trials to identify medication and psychotherapy interventions proven to be efficacious for PTSD. We then developed a semi-structured clinician interview called the Emory Treatment Resistance Interview for PTSD (E-TRIP). The E-TRIP includes clinician-administered questions to assess the adequacy and benefit derived from past treatment trials. For each adequately delivered treatment to which the patient failed to respond, a score is assigned depending on the strength of evidence supporting the treatment's efficacy. The E-TRIP provides a comprehensive assessment of prior PTSD treatments that should prove valuable for researchers studying TR-PTSD and evaluating the efficacy of new treatments for patients with PTSD. The E-TRIP is not intended to guide treatment; rather, the tool quantifies the level of treatment resistance in patients with PTSD in order to standardize TR-PTSD in the research domain.

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center