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Psychiatry Res. 2015 Feb 28;231(2):184-6. doi: 10.1016/j.pscychresns.2014.11.001. Epub 2014 Nov 8.

Brain structure in narcissistic personality disorder: a VBM and DTI pilot study.

Author information

1
Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany. Electronic address: igor.nenadic@uni-jena.de.
2
Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.
3
Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.
4
Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany; Department of Neurology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.

Abstract

We analysed T1-weighted MRI scans using voxel-based morphometry (VBM) and tract-based spatial statistics (TBBS) on diffusion tensor images (DTI) in narcissistic personality disorder (NaPD) patients and healthy controls. Grey matter deficits include right prefrontal and bilateral medial prefrontal/anterior cingulate cortices, and decreased fractional anisotropy in right frontal lobe white matter.

KEYWORDS:

Diffusion tensor imaging (DTI); Narcissistic personality disorder; Voxel-based morphometry (VBM)

[Indexed for MEDLINE]

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