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Lupus. 2015 May;24(6):633-7. doi: 10.1177/0961203314560426. Epub 2014 Dec 7.

Simultaneous presentation of acute disseminated encephalomyelitis (ADEM) and systemic lupus erythematosus (SLE) after enteroviral infection: can ADEM present as the first manifestation of SLE?

Author information

1
Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
2
Department of Radiology, Keimyung University School of Medicine, Daegu, Korea.
3
Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea mdkim9111@gmail.com.

Abstract

Central Nervous System (CNS) involvement of Systemic Lupus Erythematosus (SLE) includes a broad range of neuropsychiatric syndromes. Acute Disseminated Encephalomyelitis (ADEM) is a demyelinating CNS disorder characterized by encephalopathy and multifocal lesions predominantly involving the white matter on brain magnetic resonance imaging. ADEM associated with SLE has been only rarely reported. We report an unusual case of a 17-year-old girl who developed ADEM after enteroviral infection as the first manifestation of SLE. The authors emphasize that the patient's illness was preceded by enteroviral infection and that ADEM occurred before any other symptoms of SLE, which makes this case unique.

KEYWORDS:

Systemic lupus erythematosus; acute disseminated encephalomyelitis; enteroviral infection

PMID:
25488421
DOI:
10.1177/0961203314560426
[Indexed for MEDLINE]

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