Format

Send to

Choose Destination
Pediatr Dermatol. 2015 Jan-Feb;32(1):e15-7. doi: 10.1111/pde.12473. Epub 2014 Dec 9.

Metabolic acidosis in an infant associated with permethrin toxicity.

Author information

1
Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey.

Abstract

Pyrethroids are broad-spectrum insecticides. Permethrin intoxication due to topical application has not been documented in humans. We report a 20-month-old infant who had used 5% permethrin lotion topically for scabies treatment. Approximately 60 mL (20 mL/day) was used and after the third application he developed agitation, nausea, vomiting, respiratory distress, tachycardia, and metabolic acidosis. His clinical symptoms and metabolic acidosis normalized within 20 hours. His follow-up was unremarkable. Toxicity of permethrin is rare, and although permethrin is a widely and safely used topical agent in the treatment of scabies and lice, inappropriate use may rarely cause toxicity. Moreover, in cases of unexplained metabolic acidosis, topically applied medications should be carefully investigated.

PMID:
25487692
DOI:
10.1111/pde.12473
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center