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Am J Perinatol. 2015 Jun;32(7):615-20. doi: 10.1055/s-0034-1386634. Epub 2014 Dec 8.

The influence of gestational weight gain on the development of gestational hypertension in obese women.

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Perinatal Diagnostic Center, Baptist Health Lexington, Lexington, Kentucky.
Department of Maternal-Fetal Medicine, Carolinas Medical Center, Charlotte, North Carolina.
Department of Clinical Research, Alere Women's and Children's Health, Atlanta, Georgia.
College of Charleston, Charleston, South Carolina.
Department of Obstetrics and Gynecology, University of Texas Medical School at Houston, Houston, Texas.



The objective of this study was to examine the influence of gestational weight gain on the development of gestational hypertension/preeclampsia (GHTN/PE) in women with an obese prepregnancy body mass index (BMI).


Obese women with a singleton pregnancy enrolled at < 20 weeks were studied. Data were classified according to reported gestational weight gain (losing weight, under-gaining, within target, and over-gaining) from the recommended range of 11 to 9.7 kg and by obesity class (class 1 = BMI 30-34.9 kg/m(2), class 2 = 35-39.9 kg/m(2), class 3 = 40-49.9 kg/m(2), and class 4 ≥ 50 kg/m(2)). Rates of GHTN/PE were compared by weight gain group overall and within obesity class using Pearson chi-square statistics.


For the 27,898 obese women studied, rates of GHTN/PE increased with increasing class of obesity (15.2% for class 1 and 32.0% for class 4). The incidence of GHTN/PE in obese women was not modified with weight loss or weight gain below recommended levels. Overall for obese women, over-gaining weight was associated with higher rates of GHTN/PE compared with those with a target rate for obesity classes 1 to 3 (each p < 0.001).


Below recommended gestational weight gain did not reduce the risk for GHTN/PE in women with an obese prepregnancy BMI. These data support a gestational weight gain goal ≤ 9.7 kg in obese gravidas.

[Indexed for MEDLINE]

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