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Haematologica. 2015 Mar;100(3):e110-3. doi: 10.3324/haematol.2014.118786. Epub 2014 Dec 5.

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells.

Author information

1
Department of Internal Medicine V, University of Heidelberg, Germany.
2
Department of Internal Medicine V, University of Heidelberg, Germany Department of Molecular & Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
3
Centre for Myeloma Research, Division of Molecular Pathology, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, UK.
4
INSERM, Unité 1040, Institut de Recherche en Biothérapie, Centre Hospitalier Universitaire de Montpellier, Hôpital Saint Eloi, Avenue Augustin Fliche, 34295 Montpellier, France.
5
German Cancer Research Center, Heidelberg, Germany Center for Primary Health Care Research, Lund University, Malmo, Sweden.
6
German Cancer Research Center, Heidelberg, Germany.
7
Molecular and Population Genetics, Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK.
8
Haematological Malignancy Diagnostic Service Laboratory, St James University Hospital, Leeds, UK.
9
Department of Haematology, University College London Hospital, UK.
10
Institute of Human Genetics, University of Bonn, Germany Division of Medical Genetics, Department of Biomedicine, University of Basel, Switzerland.
11
Institute of Human Genetics, University of Bonn, Germany Department of Genomics, Life & Brain Center, University of Bonn, Germany.
12
Department of Internal Medicine V, University of Heidelberg, Germany National Centre for Tumor Diseases, Heidelberg, Germany.
13
Department of Internal Medicine V, University of Heidelberg, Germany National Centre for Tumor Diseases, Heidelberg, Germany dirk.hose@med.uni-heidelberg.de.

KEYWORDS:

eQTL; multiple myeloma; risk; single nucleotide polymorphism

PMID:
25480495
PMCID:
PMC4349291
DOI:
10.3324/haematol.2014.118786
[Indexed for MEDLINE]
Free PMC Article

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