Format

Send to

Choose Destination
Rheumatology (Oxford). 2015 Apr;54(4):572-87. doi: 10.1093/rheumatology/keu394. Epub 2014 Dec 3.

High-risk pregnancy and the rheumatologist.

Author information

1
Division of Women's Health, Women's Health Academic Centre, King's College London, King's Health Partners, London, UK.
2
Division of Women's Health, Women's Health Academic Centre, King's College London, King's Health Partners, London, UK. catherine.nelson-piercy@gstt.nhs.uk.

Abstract

Rheumatologists are increasingly involved in the care of young women who, in the age of biologic therapy, are now gaining control of their rheumatic diseases and attempting pregnancy. With careful planning, most women with rheumatic diseases have successful pregnancies. This article focuses specifically on the highest-risk pregnancies and controversial areas. We discuss the women at risk of complications, the types of maternal and fetal complications, the treatments that can be used in pregnancy (and breastfeeding) and longer-term outcomes that could affect the mother. SLE, RA, ANCA-associated vasculitides, large vessel vasculitis (e.g. Takayasu's) and other CTDs (e.g. scleroderma) are among the conditions covered. The evidence and controversies regarding the recommendations for the use of biologics in pregnancy are discussed. The role of the rheumatologist in pregnancy planning and caring for the pregnant and post-partum woman as part of the multidisciplinary team is discussed.

KEYWORDS:

anti-phospholipid antibodies; biologics; connective tissue diseases; pregnancy complications; vasculitis

PMID:
25477056
DOI:
10.1093/rheumatology/keu394
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center