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World J Surg Oncol. 2014 Dec 5;12:374. doi: 10.1186/1477-7819-12-374.

Primitive neuroectodermal tumor (PNET) of the lung in an adult woman.

Author information

1
Department of Clinical and Molecular Pathology and Institute of Molecular and Translational Medicine (IMTM), Faculty of Medicine and Dentistry, Palacky University, Hněvotínská 3, 775 15 Olomouc, Czech Republic. marjammg@gmail.com.

Abstract

Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed.

PMID:
25475214
PMCID:
PMC4289161
DOI:
10.1186/1477-7819-12-374
[Indexed for MEDLINE]
Free PMC Article

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