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Clin Infect Dis. 2015 Mar 15;60(6):924-7. doi: 10.1093/cid/ciu946. Epub 2014 Dec 3.

Bifidobacterium longum bacteremia in preterm infants receiving probiotics.

Author information

1
Laboratory of Microbial Genomics, Institute of Microbiology, University Hospital Center and University of Lausanne SIB Swiss Institute of Bioinformatics.
2
Service of Neonatology.
3
Laboratory of Bacteriology, Institute of Microbiology.
4
Laboratory of Microbial Genomics, Institute of Microbiology, University Hospital Center and University of Lausanne Laboratory of Bacteriology, Institute of Microbiology Infectious Diseases Service, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Switzerland.

Abstract

Administration of probiotics to premature newborns has been shown to prevent necrotizing enterocolitis and reduce all-cause mortality. In our hospital, we documented 2 cases of Bifidobacterium longum subspecies infantis bacteremia in newborns receiving probiotics. By comparative genomics, we confirmed that the strains isolated from each patient originated from the probiotics.

KEYWORDS:

Bifidobacterium; genome sequence; newborn; probiotics; sepsis

PMID:
25472946
DOI:
10.1093/cid/ciu946
[Indexed for MEDLINE]

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