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Lancet. 2015 Mar 14;385(9972):977-1010. doi: 10.1016/S0140-6736(14)62038-9. Epub 2014 Nov 26.

Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2).

Collaborators (496)

Bouzbid S, Hamdi-Chérif M, Zaidi Z, Bah E, Swaminathan R, Nortje SH, Stefan CD, El Mistiri MM, Bayo S, Malle B, Manraj SS, Sewpaul-Sungkur R, Fabowale A, Ogunbiyi OJ, Bradshaw D, Somdyala NI, Abdel-Rahman M, Jaidane L, Mokni M, Kumcher I, Moreno F, González MS, Laura E, Pugh FV, Torrent ME, Carballo Quintero B, Fita R, Garcilazo D, Giacciani PL, Diumenjo MC, Laspada WD, Green MA, Lanza MF, Ibañez SG, Lima CA, Lobo E, Daniel C, Scandiuzzi C, De Souza PC, Del Pino K, Laporte C, Curado MP, de Oliveira JC, Veneziano CL, Veneziano DB, Alexandre TS, Verdugo AS, Koifman S, Azevedo e Silva G, Galaz JC, Moya JA, Herrmann DA, Jofre AM, Uribe CJ, Bravo LE, Lopez Guarnizo G, Jurado DM, Yepes MC, Galán YH, Torres P, Martínez-Reyes F, Jaramillo L, Quinto R, Cueva P, Yépez J, Torres-Cintrón CR, Tortolero-Luna G, Alonso R, Barrios E, Russell C, Shack L, Coldman AJ, Woods RR, Noonan G, Turner D, Kumar E, Zhang B, McCrate FR, Ryan S, Hannah H, Dewar RA, MacIntyre M, Lalany A, Ruta M, Marrett L, Nishri DE, Vriends KA, Bertrand C, Louchini R, Robb KI, Stuart-Panko H, Demers S, Wright S, George J, Shen X, Brockhouse JT, O'Brien DK, Almon L, Young JL, Bates J, Rycroft R, Mueller L, Phillips C, Ryan H, Walrath J, Schwartz A, Vigneau F, MacKinnon JA, Wohler B, Bayakly R, Ward KC, Davidson-Allen K, Glaser S, West D, Green MD, Hernandez BY, Johnson CJ, Lynch CF, McKeen KM, Huang B, Tucker TC, Deapen D, Liu L, Hsieh MC, Wu XC, Stern K, Gershman ST, Knowlton RC, Copeland G, Spivak G, Rogers DB, Lemons D, Williamson LL, Hood M, Jerry H, Hosain GM, Rees JR, Pawlish KS, Stroup A, Key C, Wiggins C, Kahn AR, Schymura MJ, Leung G, Rao C, Giljahn L, Warther B, Pate A, Patil M, Shipley DK, Esterly M, Otto RD, Fulton JP, Rousseau DL, Janes TA, Schwartz SM, Bolick SW, Hurley DM, Tenney RA, Whiteside MA, Hakenewerth A, Williams MA, Herget K, Sweeney C, Martin J, Wang S, Harrelson MG, Keitheri Cheteri MB, Hudson AG, Borchers R, Stephenson L, Espinoza JR, Weir HK, Edwards BK, Wang N, Yang L, Chen JS, Song GH, Gu XP, Zhang P, Ge HM, Zhao DL, Zhang JH, Zhu FD, Tang JG, Shen Y, Wang J, Li QL, Yang SP, Dong JM, Li WW, Cheng LP, Chen JG, Huang QH, Huang SQ, Guo GP, Wei K, Chen WQ, Zeng H, Demetriou AW, Pavlou P, Mang WK, Ngan KC, Swaminathan R, Kataki AC, Krishnatreya M, Jayalekshmi PA, Sebastian P, Sapkota SD, Verma Y, Nandakumar A, Suzanna E, Keinan-Boker L, Silverman BG, Ito H, Hattori M, Sugiyama H, Utada M, Katayama K, Natsui S, Matsuda T, Nishino Y, Koike T, Ioka A, Nakata K, Kosa K, Oki I, Shibata A, Nimri O, Ab Manan A, Bhoo Pathy N, Ochir C, Tuvshingerel S, Al Khater AM, El Mistiri MM, Al-Eid H, Jung KW, Won YJ, Park S, Chiang CJ, Lai MS, Suwanrungruang K, Wiangnon S, Daoprasert K, Pongnikorn D, Geater SL, Sriplung H, Eser S, Yakut CI, Hackl M, Zielonke N, Mühlböck H, Oberaigner W, Piñeros M, Zborovskaya AA, Henau K, Van Eycken L, Dimitrova N, Valerianova Z, Šekerija M, Znaor A, Zvolský M, Engholm G, Storm H, Aareleid T, Mägi M, Malila N, Seppä K, Velten M, Cornet E, Troussard X, Bouvier AM, Faivre J, Guizard AV, Bouvier V, Launoy G, Arveux P, Maynadié M, Mounier M, Woronoff AS, Daoulas M, Clavel J, Le Guyader-Peyrou S, Monnereau A, Trétarre B, Colonna M, Delacour-Billon S, Molinié F, Bara S, Degré D, Ganry O, Lapôtre-Ledoux B, Grosclaude P, Lutz JM, Belot A, Estève J, Forman D, Sassi F, Stabenow R, Eberle A, Nennecke A, Kieschke J, Sirri E, Kajueter H, Emrich K, Zeissig SR, Holleczek B, Eisemann N, Katalinic A, Brenner H, Asquez RA, Kumar V, Ólafsdóttir EJ, Tryggvadóttir L, Comber H, Walsh PM, Sundseth H, Dal Cappello T, Mazzoleni G, Giacomin A, Castaing M, Sciacca S, Sutera A, Corti M, Gola G, Ferretti S, Serraino D, Zucchetto A, Lillini R, Vercelli M, Busco S, Pannozzo F, Vitarelli S, Ricci P, Pascucci V, Autelitano M, Cirilli C, Federico M, Fusco M, Vitale MF, Usala M, Cusimano R, Vitale F, Michiara M, Sgargi P, Sacerdote C, Tumino R, Mangone L, Falcini F, Cremone L, Budroni M, Cesaraccio R, Madeddu A, Tisano F, Maspero S, Tessandori R, Candela G, Scuderi T, Piffer S, Rosso S, Zanetti R, Caldarella A, Crocetti E, La Rosa F, Stracci F, Contiero P, Tagliabue G, Zambon P, Baili P, Berrino F, Gatta G, Sant M, Capocaccia R, De Angelis R, Verdecchia A, Liepina E, Maurina A, Smailyte G, Agius D, Calleja N, Siesling S, Laronningen S, Møller B, Dyzmann-Sroka A, Trojanowski M, Góźdż S, Mężyk R, Gądalska-Lampart M, Radziszewska AU, Didkowska J, Wojciechowska U, Błaszczyk J, Kępska K, Bielska-Lasota M, Forjaz G, Rego RA, Bastos J, Antunes L, Bento MJ, da Costa Miranda AM, Mayer-da-Silva A, Coza D, Todescu AI, Krasilnikov A, Valkov M, Adamcik J, Safaei Diba C, Primic Žakelj M, Žagar T, Stare J, Almar E, Mateos A, Argüelles MV, Quirós JR, Bidaurrazaga J, Larrañaga N, Díaz García JM, Marcos AI, Marcos-Gragera R, Vilardell Gil ML, Molina E, Sánchez MJ, Ramos Montserrat M, Chirlaque MD, Navarro C, Ardanaz E, Felipe Garcia S, Peris-Bonet R, Galceran J, Khan S, Lambe M, Camey B, Bouchardy C, Usel M, Ess SM, Hermann C, Levi FG, Maspoli-Conconi M, Kuehni CE, Mitter VR, Bordoni A, Spitale A, Chiolero A, Konzelmann I, Dehler SI, Laue RI, Meechan D, Poole J, Greenberg D, Rashbass J, Davies E, Linklater K, Morris E, Moran T, Bannon F, Gavin A, Black RJ, Brewster DH, Roche M, McPhail S, Verne J, Murphy M, Stiller C, Huws DW, White C, Lawrence G, Brook C, Wilkinson J, Finan P, Ahn JV, Allemani C, Bonaventure A, Carreira H, Coleman MP, Harewood R, Rachet B, Sanz N, Spika D, Wang XS, Stephens R, Butler J, Peake M, Chalker E, Newman L, Baker D, Soeberg MJ, Scott C, Stokes BC, Venn A, Farrugia H, Giles GG, Threlfall T, Currow D, You H, Lewis C, Miles SA.

Erratum in

  • Lancet. 2015 Mar 14;385(9972):946.

Abstract

BACKGROUND:

Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.

METHODS:

Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights.

FINDINGS:

5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease.

INTERPRETATION:

International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems.

FUNDING:

Canadian Partnership Against Cancer (Toronto, Canada), Cancer Focus Northern Ireland (Belfast, UK), Cancer Institute New South Wales (Sydney, Australia), Cancer Research UK (London, UK), Centers for Disease Control and Prevention (Atlanta, GA, USA), Swiss Re (London, UK), Swiss Cancer Research foundation (Bern, Switzerland), Swiss Cancer League (Bern, Switzerland), and University of Kentucky (Lexington, KY, USA).

PMID:
25467588
PMCID:
PMC4588097
DOI:
10.1016/S0140-6736(14)62038-9
[Indexed for MEDLINE]
Free PMC Article
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