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Curr Opin Microbiol. 2014 Dec;22:66-72. doi: 10.1016/j.mib.2014.09.016.

Spatial organization of bacterial chromosomes.

Author information

1
Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA

Abstract

Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a deeper characterization of chromosome dynamics in the original model systems have provided a broader and more complete picture of both chromosome organization and the activities that generate the observed spatial patterns. Here, we summarize these different patterns highlighting similarities and differences and discuss the protein factors that help establish and maintain them.

PMID:
25460798
PMCID:
PMC4359757
DOI:
10.1016/j.mib.2014.09.016
[Indexed for MEDLINE]
Free PMC Article

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