Format

Send to

Choose Destination
Clin Perinatol. 2014 Dec;41(4):945-55. doi: 10.1016/j.clp.2014.08.012. Epub 2014 Sep 27.

Preventing herpes simplex virus in the newborn.

Author information

1
Division of Pediatric Infectious Diseases, The University of Alabama at Birmingham, 1600 Seventh Avenue South, CHB 308, Birmingham, AL 35233, USA.
2
Division of Pediatric Infectious Diseases, The University of Alabama at Birmingham, 1600 Seventh Avenue South, CHB 303, Birmingham, AL 35233, USA. Electronic address: dkimberlin@peds.uab.edu.

Abstract

Genital herpes simplex virus (HSV) infections are very common worldwide. Approximately 22% of pregnant women are infected genitally with HSV, and most of them are unaware of this. The most devastating consequence of maternal genital herpes is HSV disease in the newborn. Although neonatal HSV infections remain uncommon, due to the significant morbidity and mortality associated with the infection, HSV infection in the newborn is often considered in the differential diagnosis of ill neonates. This review summarizes the epidemiology and management of neonatal HSV infections and discusses strategies to prevent HSV infection in the newborn.

KEYWORDS:

Acyclovir; Antiviral therapy; Genital herpes; HSV; PCR

PMID:
25459782
PMCID:
PMC4386734
DOI:
10.1016/j.clp.2014.08.012
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center