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Sleep Med Rev. 2015 Aug;22:78-87. doi: 10.1016/j.smrv.2014.10.005. Epub 2014 Oct 18.

Sleep, sleep disturbance, and fertility in women.

Author information

1
Department of Psychology, Drexel University, USA. Electronic address: jdk29@drexel.edu.
2
Department of Psychiatry, Behavioral Sleep Medicine Program, University of Pennsylvania, USA.
3
Department of Psychology, Drexel University, USA.
4
Department of Obstetrics and Gynecology at the Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, USA.

Abstract

Sleep and sleep disturbances are increasingly recognized as determinants of women's health and well-being, particularly in the context of the menstrual cycle, pregnancy, and menopause. At present, however, little is known about whether fertility is affected by sleep quantity and quality. That is, to what degree, and by what mechanisms, do sleep and/or its disturbances affect fertility? The purpose of this review is to synthesize what is known about sleep disturbances in relation to reproductive capacity. A model is provided, whereby stress, sleep dysregulation, and circadian misalignment are delineated for their potential relevance to infertility. Ultimately, if it is the case that sleep disturbance is associated with infertility, new avenues for clinical intervention may be possible.

KEYWORDS:

Circadian; Infertility; Insomnia; Reproductive health; Reproductive hormones; Sleep; Sleep disturbance; Women's health

PMID:
25458772
PMCID:
PMC4402098
DOI:
10.1016/j.smrv.2014.10.005
[Indexed for MEDLINE]
Free PMC Article

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