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Chest. 2014 Dec;146(6):e190-e194. doi: 10.1378/chest.14-0394.

Talc pleurodesis through indwelling pleural catheters for malignant pleural effusions: retrospective case series of a novel clinical pathway.

Author information

1
Guy's and St Thomas' NHS Trust, London, England.
2
Guy's and St Thomas' NHS Trust, London, England. Electronic address: Hughip@gmail.com.
3
King's College London, London, England.

Abstract

Malignant pleural effusions cause significant morbidity, but there is no gold standard minimally invasive treatment. A new therapeutic approach combines talc pleurodesis and indwelling pleural catheters (IPCs) to enable outpatient management. This case series summarizes the safety and efficacy data of all patients (24) with a symptomatic malignant pleural effusion who underwent talc pleurodeses via IPCs between December 2010 and July 2013. Successful pleurodesis was achieved in 22 procedures (92%). There was one empyema, one hydropneumothorax, one recurrent effusion, and two minor complications: one drain site wound infection and one complaint of chest pain. Twenty-two procedures (92%) were performed in the outpatient setting. This report confirms the safety and efficacy of administering talc slurry through IPCs in an outpatient setting. Studies in a larger cohort are necessary to define the role of this novel approach in the treatment algorithm of patients with this condition.

PMID:
25451360
DOI:
10.1378/chest.14-0394
[Indexed for MEDLINE]

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