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J Gynecol Obstet Biol Reprod (Paris). 2014 Dec;43(10):764-75. doi: 10.1016/j.jgyn.2014.09.011. Epub 2014 Nov 6.

[Epidemiology of loss pregnancy].

[Article in French]

Author information

1
Pôle de gynécologie-obstétrique reproduction humaine, CHU Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France; EA7281-R2D2, faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France. Electronic address: adelabaere@chu-clermontferrand.fr.
2
Service de gynécologie-obstétrique, centre hospitalier Poissy-Saint-Germain, 10, rue du Champ-Gaillard, 78300 Poissy, France; EA 7285 risques cliniques et sécurité en santé des femmes, université Versailles-Saint-Quentin-en-Yvelines, 78000 Versailles, France.
3
Service de gynécologie-obstétrique, hôpital Antoine-Béclère, GHU Sud, AP-HP, 157, rue de la Porte-de-Trivaux, 92140 Clamart, France.
4
Service de gynécologie-obstétrique et médecine de la reproduction, CHU de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 9, France.
5
Unité de cytogénétique, CHI Poissy-Saint-Germain, 10, rue du Champ-Gaillard, 78300 Poissy, France; EA 2493, UFR des sciences de la santé Simone-Veil, université Versailles-Saint-Quentin-en-Yvelines, 78000 Versailles, France.
6
Service de gynécologie-obstétrique, hôpital Nord, Assistance publique des Hôpitaux de Marseille (APHM), chemin des Bourrely, 13915 Marseille cedex 20, France; Faculté de médecine, université d'Aix-Marseille (AMU), 27, boulevard Jean-Moulin, 13385 Marseille cedex 05, France.
7
Service de gynécologie-obstétrique, centre hospitalier Poissy-Saint-Germain, 10, rue du Champ-Gaillard, 78300 Poissy, France.
8
Maternité, université Lille Nord de France, hôpital Jeanne-de-Flandre, CHRU de Lille, 59037 Lille cedex, France; EA 2694, université Lille Nord de France, CHRU de Lille, 59037 Lille cedex, France.
9
Pôle de gynécologie-obstétrique reproduction humaine, CHU Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France; EA 4681 PEPRADE, faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.
10
Pôle de gynécologie-obstétrique reproduction humaine, CHU Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France; EA7281-R2D2, faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.
11
Pôle de gynécologie-obstétrique reproduction humaine, CHU Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France; EA7281-R2D2, faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France; EA 4681 PEPRADE, faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.

Abstract

OBJECTIVES:

Study of epidemiology of pregnancy loss.

MATERIALS AND METHOD:

A systematic review of the literature was performed using Pubmed and the Cochrane library databases and the guidelines from main international societies.

RESULTS:

The occurrence of first trimester miscarriage is 12% of pregnancies and 25% of women. Miscarriage risk factors are ages of woman and man, body mass index greater than or equal to 25kg/m(2), excessive coffee drinking, smoking and alcohol consumption, exposure to magnetic fields and ionizing radiation, history of abortion, some fertility disorders and impaired ovarian reserve. Late miscarriage (LM) complicates less than 1% of pregnancies. Identified risk factors are maternal age, low level of education, living alone, history of previous miscarriage, of premature delivery and of previous termination of pregnancy, any uterine malformation, trachelectomy, existing bacterial vaginosis, amniocentesis, a shortened cervix and a dilated cervical os with prolapsed membranes. Fetal death in utero has a prevalence of 2% in the world and 5/1000 in France. Its main risk factors are detailed in the chapter.

KEYWORDS:

Avortement spontané; Fausse couche; Fetal loss; Miscarriage; Mort fœtale in utero; Perte de grossesse; Perte fœtale; Pregnancy loss; Spontaneous abortion; Stillbirth

PMID:
25447360
DOI:
10.1016/j.jgyn.2014.09.011
[Indexed for MEDLINE]
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