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Infect Genet Evol. 2014 Dec;28:296-303. doi: 10.1016/j.meegid.2014.10.017. Epub 2014 Oct 27.

Co-circulation of soricid- and talpid-borne hantaviruses in Poland.

Author information

1
Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
2
Department of Teacher Training and Biodiversity Studies, Faculty of Biology and Environmental Protection, University of Łódź, S. Banacha Street 1/3, 90-237 Łódź, Poland.
3
Department of Experimental Zoology and Evolutionary Biology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland.
4
Department of Algology and Mycology, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland.
5
Department of Molecular Pathology and Neuropathology, Medical University of Łódź, Czechoslowacka Street 8/10, 92-216 Łódź, Poland.
6
Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA. Electronic address: ryanagih@hawaii.edu.

Abstract

Previously, we reported the discovery of a genetically distinct hantavirus, designated Boginia virus (BOGV), in the Eurasian water shrew (Neomys fodiens), as well as the detection of Seewis virus (SWSV) in the Eurasian common shrew (Sorex araneus), in central Poland. In this expanded study of 133 shrews and 69 moles captured during 2010-2013 in central and southeastern Poland, we demonstrate the co-circulation of BOGV in the Eurasian water shrew and SWSV in the Eurasian common shrew, Eurasian pygmy shrew (Sorex minutus) and Mediterranean water shrew (Neomys anomalus). In addition, we found high prevalence of Nova virus (NVAV) infection in the European mole (Talpa europaea), with evidence of NVAV RNA in heart, lung, liver, kidney, spleen and intestine. The nucleotide and amino acid sequence variation of the L segment among the SWSV strains was 0-18.8% and 0-5.4%, respectively. And for the 38 NVAV strains from European moles captured in Huta Dłutowska, the L-segment genetic similarity ranged from 94.1%-100% at the nucleotide level and 96.3%-100% at the amino acid level. Phylogenetic analyses showed geographic-specific lineages of SWSV and NVAV in Poland, not unlike that of rodent-borne hantaviruses, suggesting long-standing host-specific adaptation. The co-circulation and distribution of BOGV, SWSV and NVAV in Poland parallels findings of multiple hantavirus species co-existing in their respective rodent reservoir species elsewhere in Europe. Also, the detection of SWSV in three syntopic shrew species resembles spill over events observed among some rodent-borne hantaviruses.

KEYWORDS:

Hantavirus; Neomys; Phylogeny; Poland; Sorex; Talpa

PMID:
25445646
PMCID:
PMC4257849
DOI:
10.1016/j.meegid.2014.10.017
[Indexed for MEDLINE]
Free PMC Article

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