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Prev Med. 2015 Jul;76 Suppl:S22-32. doi: 10.1016/j.ypmed.2014.11.003. Epub 2014 Nov 20.

Effectiveness of psychological and/or educational interventions to prevent the onset of episodes of depression: A systematic review of systematic reviews and meta-analyses.

Author information

1
Centro de Salud El Palo, Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Investigación del Distrito de Atención Primaria Málaga-Guadalhorce, Departamento de Medicina Preventiva y Salud Pública, Universidad de Málaga, Málaga, Spain. Electronic address: jabellon@uma.es.
2
Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Investigación del Distrito de Atención Primaria Málaga-Guadalhorce, Málaga, Spain. Electronic address: predictmalaga@hotmail.com.
3
Departamento de Psicología Psicología y Trabajo Social, Universidad de Loyola, Sevilla, Spain. Electronic address: emotrico@uloyola.es.
4
Departamento de Personalidad, Evaluación Tratamiento Psicológico, Universidad de Málaga, Málaga, Spain. Electronic address: aromore@uma.es.
5
Centre for Disability Research Policy - Brain Mind Research Institute, Faculty of Health Sciences, University of Sydney, Sydney, Australia; Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona, Spain. Electronic address: ana.fernandez@sydney.edu.au.
6
Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona, Spain. Electronic address: aserrano@pssjd.org.
7
Institut Universitari d'Investigació en Atenció Primària (IDIAP) Jordi Gol, Barcelona, Spain. Electronic address: ezabaleta@idiapjgol.org.
8
Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Investigación del Distrito de Atención Primaria Málaga-Guadalhorce, Málaga, Spain. Electronic address: soniafundacionimabis@hotmail.com.

Abstract

OBJECTIVE:

To determine the effectiveness of psychological and/or educational interventions to prevent the onset of episodes of depression.

METHODS:

Systematic review of systematic reviews and meta-analyses (SR/MA). We searched PubMed, PsycINFO, Cochrane Database of Systematic Reviews, OpenGrey, and PROSPERO from their inception until February 2014. Two reviewers independently evaluated the eligibility criteria of all SR/MA, abstracted data, and determined bias risk (AMSTAR).

RESULTS:

Twelve SR/MA (156 non-repeated trials and 56,158 participants) were included. Of these, 142 (91%) were randomized-controlled, 13 (8.3%) controlled trials, and 1 (0.6%) had no control group. Five SR/MA focused on children and adolescents, four on specific populations (women after childbirth, of low socioeconomic status, or unfavorable circumstances; patients with severe traumatic physical injuries or stroke) and three addressed the general population. Nine (75%) SR/MA concluded that interventions to prevent depression were effective. Of the 156 trials, 137 (87.8%) reported some kind of effect size calculation. Effect sizes were small in 45 (32.8%), medium in 26 (19.1%), and large in 25 (18.2%) trials; 41 (29.9%) trials were not effective. Of the 141 trials for which follow-up periods were available, only 34 (24.1%) exceeded 12 months.

CONCLUSION:

Psychological and/or educational interventions to prevent onset of episodes of depression were effective, although most had small or medium effect sizes.

KEYWORDS:

Depression; Primary prevention; Systematic review

PMID:
25445331
DOI:
10.1016/j.ypmed.2014.11.003
[Indexed for MEDLINE]

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