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J Infect Chemother. 2015 Mar;21(3):212-4. doi: 10.1016/j.jiac.2014.08.029. Epub 2014 Oct 23.

Multidrug-resistant Acinetobactor baumannii isolated from a traveler returned from Brunei.

Author information

1
Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan; Disease Control and Prevention Center, Japan; Department of Infectious Diseases, Research Institute, Japan.
2
Disease Control and Prevention Center, Japan.
3
Disease Control and Prevention Center, Japan; Department of Infectious Diseases, Research Institute, Japan.
4
Department of Infectious Diseases, Research Institute, Japan.
5
Department of Clinical Laboratory, Japan.
6
Infection Control and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
7
Department of Infectious Diseases, Research Institute, Japan. Electronic address: tkirikae@ri.ncgm.go.jp.

Abstract

We report a case of multidrug-resistant (MDR) Acinetobactor baumannii isolates obtained from a traveler returned from Brunei. Whole-genome sequencing analysis revealed that the isolates harbored blaOxA-23 and armA. The minimum inhibitory concentrations of antibiotics against the strain were as follows: imipenem, 32 μg/ml; meropenem, 32 μg/ml; ciprofloxacin, 16 μg/ml; amikacin, ≧ 1024 μg/ml; arbekacin, ≧ 1024 μg/ml; aztreonam, 64 μg/ml; colistin, 4 μg/ml. A. baumannii harboring both blaOxA-23 and armA is rarely reported in Japan, and, to the best of our knowledge, this is the second report of A. baumannii harboring both resistant genes in Japan.

KEYWORDS:

16S rRNA methylase; Acinetobacter baumannii; Antimicrobial resistance; Carbapenemase; armA; bla(OxA-23)

PMID:
25444675
DOI:
10.1016/j.jiac.2014.08.029
[Indexed for MEDLINE]

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