Format

Send to

Choose Destination
J Psychosom Res. 2014 Nov;77(5):415-9. doi: 10.1016/j.jpsychores.2014.06.016. Epub 2014 Jul 9.

Intranasal oxytocin enhances positive self-attribution in healthy men.

Author information

1
Department of Psychology, Laboratory for Biological and Personality Psychology, University of Freiburg, D-79104 Freiburg, Germany. Electronic address: valentina.colonnello@psychologie.uni-freiburg.de.
2
Department of Psychology, Laboratory for Biological and Personality Psychology, University of Freiburg, D-79104 Freiburg, Germany; Freiburg Brain Imaging Center, University Medical Center, University of Freiburg, D-79106 Freiburg, Germany. Electronic address: heinrichs@psychologie.uni-freiburg.de.

Abstract

OBJECTIVE:

A growing body of studies consistently demonstrates that social responsiveness toward others is influenced by the neurohormone oxytocin. However, the potential role of oxytocin for self-perception remains relatively unexplored. Thus, we investigated whether oxytocin administration influences the self-attribution of positive and negative adjectives at the early, effortful stage of self-related information processing.

METHODS:

Sixty healthy male participants received either 24I.U. oxytocin or a placebo in a randomized double-blind study before completing a sorting task, in which they were instructed to co-classify, as fast as possible, positive and negative adjectives into either self or non-self categories.

RESULTS:

Oxytocin-treated participants reported stronger positive attitudes toward themselves compared to placebo.

CONCLUSIONS:

The present findings demonstrate that oxytocin administration influences the early stage of self-related information processing and suggests that the oxytocinergic system might be involved in psychopathological conditions characterized by a negative representation of self.

KEYWORDS:

Intranasal; Oxytocin; Self; Social cognition

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center