Polycystic ovary syndrome: a review for dermatologists: Part II. Treatment

J Am Acad Dermatol. 2014 Nov;71(5):859.e1-859.e15; quiz 873-4. doi: 10.1016/j.jaad.2014.05.009. Epub 2014 Oct 15.

Abstract

Dermatologists are in a key position to treat the manifestations of polycystic ovary syndrome (PCOS). The management of PCOS should be tailored to each woman's specific goals, reproductive interests, and particular constellation of symptoms. Therefore, a multidisciplinary approach is recommended. In part II of this continuing medical education article, we present the available safety and efficacy data regarding treatments for women with acne, hirsutism, and androgenetic alopecia. Therapies discussed include lifestyle modification, topical therapies, combined oral contraceptives, antiandrogen agents, and insulin-sensitizing drugs. Treatment recommendations are made based on the current available evidence.

Keywords: acne; androgenetic alopecia; combined oral contraceptive pills; cyproterone acetate; drospirenone; hirsutism; insulin-sensitizing drugs; polycystic ovary syndrome; spironolactone.

Publication types

  • Review

MeSH terms

  • 5-alpha Reductase Inhibitors / therapeutic use
  • Acne Vulgaris / drug therapy*
  • Alopecia / drug therapy*
  • Androgen Antagonists / therapeutic use
  • Contraceptives, Oral, Combined / adverse effects
  • Contraceptives, Oral, Combined / therapeutic use*
  • Dermatology*
  • Female
  • Finasteride / therapeutic use
  • Flutamide / therapeutic use
  • Hirsutism / drug therapy*
  • Hirsutism / surgery
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Life Style
  • Metformin / therapeutic use
  • Mineralocorticoid Receptor Antagonists / therapeutic use
  • Polycystic Ovary Syndrome / therapy*
  • Spironolactone / therapeutic use
  • Thiazolidinediones / therapeutic use

Substances

  • 5-alpha Reductase Inhibitors
  • Androgen Antagonists
  • Contraceptives, Oral, Combined
  • Hypoglycemic Agents
  • Mineralocorticoid Receptor Antagonists
  • Thiazolidinediones
  • Spironolactone
  • Finasteride
  • Flutamide
  • Metformin