Reduction of opiate withdrawal symptoms with use of clonidine in a county jail

J Correct Health Care. 2015 Jan;21(1):27-34. doi: 10.1177/1078345814557630. Epub 2014 Nov 26.

Abstract

Increasingly, addicted inmates admitted to jail in New Mexico are in the process of opiate withdrawal. While the standard for opiate detoxification is a narcotic taper, correctional policy restricts opiate use for safety reasons. An alternative for withdrawal is a supportive intervention with clonidine, a non-opiate. Could clonidine be beneficial for acute opiate withdrawal symptoms in this population? Fifty-five inmates (37 male and 18 female) volunteered to participate in assessing clonidine for the reduction of withdrawal symptoms. Symptoms were assessed with the Subjective Opiate Withdrawal Scale and treated with a standard clonidine protocol. Clonidine significantly decreased the mean scores at 1 and 4 hours after medication use. Clonidine for opiate withdrawal reduces symptoms when opiate-assisted detoxification is not available.

Keywords: SOWS; clonidine; correctional health care; opiate withdrawal.

Publication types

  • Review

MeSH terms

  • Adrenergic alpha-2 Receptor Agonists / administration & dosage
  • Adrenergic alpha-2 Receptor Agonists / therapeutic use*
  • Adult
  • Clonidine / administration & dosage
  • Clonidine / therapeutic use*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Opioid-Related Disorders / drug therapy*
  • Opioid-Related Disorders / physiopathology
  • Prisons / organization & administration*
  • Substance Withdrawal Syndrome / drug therapy*
  • Substance Withdrawal Syndrome / physiopathology
  • Young Adult

Substances

  • Adrenergic alpha-2 Receptor Agonists
  • Clonidine