One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system

Cell Res. 2015 Feb;25(2):258-61. doi: 10.1038/cr.2014.158. Epub 2014 Nov 28.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Genetically Modified
  • Base Sequence
  • Clustered Regularly Interspaced Short Palindromic Repeats / genetics*
  • Embryo, Mammalian / metabolism
  • Macaca fascicularis / genetics*
  • Mutagenesis
  • RNA / metabolism
  • Tumor Suppressor Protein p53 / genetics*
  • Tumor Suppressor Protein p53 / metabolism

Substances

  • Tumor Suppressor Protein p53
  • RNA