Influence of diffusion on the stability of equilibria in a reaction-diffusion system modeling cholera dynamic

J Math Biol. 2015 Nov;71(5):1107-31. doi: 10.1007/s00285-014-0849-9. Epub 2014 Nov 26.

Abstract

A reaction-diffusion system modeling cholera epidemic in a non-homogeneously mixed population is introduced. The interaction between population and toxigenic Vibrio cholerae concentration in contaminated water has been taken into account. The existence of biologically meaningful equilibria is investigated together with their linear and nonlinear stability. Using the data collected during the Haiti cholera epidemic, a numerical simulation is performed.

Keywords: Cholera; Epidemic models; Lyapunov direct method; Reaction–diffusion systems; Stability.

MeSH terms

  • Cholera / epidemiology*
  • Cholera / transmission
  • Computer Simulation
  • Disease Reservoirs / microbiology
  • Disease Reservoirs / statistics & numerical data
  • Epidemics* / statistics & numerical data
  • Haiti / epidemiology
  • Humans
  • Linear Models
  • Mathematical Concepts
  • Models, Biological*
  • Nonlinear Dynamics
  • Vibrio cholerae / isolation & purification
  • Water Microbiology