Format

Send to

Choose Destination
J Infect Dis. 2014 Dec 15;210 Suppl 3:S616-21. doi: 10.1093/infdis/jiu459.

Vaginal microbiota and sexually transmitted infections that may influence transmission of cell-associated HIV.

Author information

1
Department of Biophysics, Johns Hopkins University, Baltimore, Maryland.

Abstract

Vaginal microbiota and sexually transmitted infections (STIs) are likely to influence the transmission of cell-associated human immunodeficiency virus (HIV). Lactic acid produced by Lactobacillus-dominated microbiota (Nugent score 0-3) will likely inhibit transmission, especially female-to-male transmission. In contrast, polymicrobial microbiota (Nugent score 4-10), community state types IV-A and IV-B, and STIs will likely increase transmission of cell-associated HIV.

KEYWORDS:

cell-associated HIV; inflammatory cytokines; lactic acid; polymicrobial microbiota

PMID:
25414415
PMCID:
PMC4303075
DOI:
10.1093/infdis/jiu459
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center