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Abdom Imaging. 2015 Aug;40(6):1769-71. doi: 10.1007/s00261-014-0301-z.

(68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer.

Author information

1
Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universit√§t M√ľnchen, Ismaninger Str. 22, 81675, Munich, Germany, matthias.eiber@tum.de.

Abstract

Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric (68)Ga-PSMA PET/MR by combining molecular and structural information.

PMID:
25412869
DOI:
10.1007/s00261-014-0301-z
[Indexed for MEDLINE]

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