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Anticancer Agents Med Chem. 2015;15(3):314-26.

Review of procedures used for the extraction of anti-cancer compounds from tropical plants.

Author information

1
School of Pharmacy, The University of Queensland, Brisbane, Australia. a.hewavitharana@pharmacy.uq.edu.au.

Abstract

Tropical plants are important sources of anti-cancer lead molecules. According to the US National Cancer Institute, out of the 3000 plants identified as active against cancer using in vitro studies, 70% are of tropical origin. The extraction of bioactive compounds from the plant materials is a fundamental step whose efficiency is critical for the success of drug discovery efforts. There has been no review published of the extraction procedures of anti-cancer compounds from tropical plants and hence the following is a critical evaluation of such procedures undertaken prior to the use of these compounds in cancer cell line studies, during the last five years. It presents a comprehensive analysis of all approaches taken to extract anti-cancer compounds from various tropical plants. (Databases searched were PubMed, SciFinder, Web of Knowledge, Scopus, Embase and Google Scholar).

PMID:
25403166
[Indexed for MEDLINE]

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